Robert Campbell, PhD bestowed the cover of the Blood Journal

Evolving evidence indicates that platelets and megakaryocytes (MKs) have unexpected activities in inflammation and infection; but whether viral infections upregulate biologically active, anti-viral immune genes in platelets and MKs is unknown. We examined anti-viral immune genes in these cells in dengue and influenza infections, viruses that are global public health threats. Using complementary biochemical, pharmacological,…

Elizabeth Leibold, PhD awarded Functional Analysis Pilot Award

Title : A functional genomics investigation hypoxia tolerance adaptation in Bajau Sea Nomads Utah Genome Project: Functional Analysis Pilot Grant Program Recently, a population of traditional marine hunter-gatherers in southeast Asia called The Bajau Sea Nomads were demonstrated to have adapted to a lifestyle based on breath-hold diving. Through thousands of years of natural selection,…

The Yost Lab has published a paper in Nature Communications titled, “Loss of Embryonic Neural Crest Derived Cardiomyocytes Causes Adult Onset Hypertrophic Cardiomyopathy in Zebrafish.”

General overview Adult-onset cardiomyopathy and heart failure in humans is a major health concern. Approximately 5.7 million adults in the US have heart failure,costing an estimated $30.7 billion each year in health care. Using zebrafish as a discovery model, we have found that disruption of a small group of specialized heart cells (called neural crest…